Coccidioidomycosis - disseminated
Alternative Names
Coccidioidomycosis - systemic
Symptoms
- Cough
- Fever
- Chills
- Headache
- Muscle stiffness
- Muscle aches
- Neck stiffness or shoulder stiffness
- Change in mental status
- Sensitivity to light
Additional symptoms that may be associated with this disease:
- Joint swelling
- Joint pain
- Skin reaction (erythema nodosum)
- Arthritis
- Ankle, feet, and leg swelling
Exams and Tests
Tests that may be done include:- CBC with differential
- Chest x-ray
- Coccidioidin skin test
- KOH test
- Serum coccidioides complement fixation titer
- Sputum culture
A biopsy of tissue may be done to determine the area of disseminated disease:
A neurological examination may show abnormalities.
References
Galgiani JN, Ampel NM, Catanzaro A, Johnson RH, Stevens DA, Williams PL. Practice guidelines for the treatment of coccidioidomycosis. Clin Infect Dis. April 2000;30:658-661.
Chiller TM. Coccidioidomycosis. Infect Dis Clin North Am. 2003; 17(1): 41-57, viii.
Murray J, Nadel J. Textbook of Respiratory Medicine. 3rd ed. Philadelphia, Pa: WB Saunders; 2000.
Mandell GL, Bennett JE, Dolin R. Principles and Practice of Infectious Diseases. 5th ed. London, UK: Churchill Livingstone; 2000:2746-2755.
Galgiani JN, Ampel N, Blair JE, et al. Coccidioidomycosis. Clin Infect Dis. 2005;41:1217-23.
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