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Achalasia

Definition

Achalasia is a disorder of the the tube that carries food from the mouth to the stomach (esophagus), which affects the ability of the esophagus to move food toward the stomach

Alternative Names

Esophageal achalasia

Causes

The main problem in achalasia is a failure of the a muscular ring where the esophagus and stomach come together (lower esophageal sphincter) to relax during swallowing.

Another part of the disorder is a lack of nerve stimulation to the muscles of the esophagus. Causes include:

  • Cancers
  • Damage to the nerves of the esophagus
  • Infection with a parasite
  • Inherited factors

As a result, the wave-like contractions of smooth muscles that normally force food through the esophagus and other parts of the digestive tract do not work as well. (These contractions are called peristalsis.)

Achalasia is a rare disorder. It may occur at any age, but is most common in middle-aged or older adults.

References

Goldman L, Ausiello DA.Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007.

Review Date: 2/20/2008
Reviewed By: Christian Stone, MD, Division of Gastroenterology, Washington University in St. Louis, School of Medicine, St. Louis, MO. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission. URAC's accreditation program is the first of its kind, requiring compliance with 53 standards of quality and accountability, verified by independent audit.

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