Perimenopause; Postmenopause
Menopause is a natural process. Treatment with hormones may be helpful if you experience debilitating symptoms such as hot flashes, night sweats, or vaginal dryness.
Discuss the decision to take hormones thoroughly with your doctor, weighing your risks against any possible benefits. Pay careful attention to the many options currently available to you that do not involve taking hormones.
If you have a uterus and decide to take estrogen, you must also take progesterone to prevent endometrial cancer (cancer of the lining of the uterus). If you do not have a uterus, progesterone is not necessary.
HORMONE REPLACEMENT THERAPY
For years, hormone replacement therapy (HRT) was the main treatment for menopause symptoms. Many physicians believed that HRT was not only good for reducing menopausal symptoms, but also reduced the risk of heart disease and bone fractures from osteoporosis. However, the results of a major study called the Women's Health Initiative has led physicians to change their recommendations.
In fact, this important study was stopped early because the health risks outweighed the benefits. Women taking the hormones did see some benefits. But they had a greatly increased risk for breast cancer, heart attacks, strokes, and blood clots.
If your symptoms are severe, you may still want to consider HRT for short-term use (2-4 years) to reduce vaginal dryness, hot flashes, and other symptoms.
To reduce the risks of estrogen replacement therapy and still gain the benefits of the treatment, your doctor may recommend:
ALTERNATIVES TO HRT
The good news is that you can take many steps to reduce your symptoms without taking hormones:
There are also some medications available to help with mood swings, hot flashes, and other symptoms. These include low doses of antidepressants such as paroxetine (Paxil), venlafaxine (Effexor), bupropion (Wellbutrin), and fluoxetine (Prozac), or clonidine, which is normally used to control high blood pressure.
Estrogen is responsible for the buildup of the lining of the uterine cavity. During the reproductive years, this buildup is shed (menstruation). This usually happens about once a month.
The menopausal decrease in estrogen prevents this buildup from occurring. However, hormones produced by the adrenal glands are converted to estrogen, and sometimes this will cause postmenopausal bleeding.
This bleeding is often nothing to worry about, but because it may also be an early indication of other problems, including cancer, your physician should always check any postmenopausal bleeding.
Decreased estrogen levels are also associated with an increased risk of developing osteoporosis and possibly an increased risk of cardiovascular disease.
Call your health care provider if:
Weismiller D. The Perimenopause and Menopause Experience: An Overview. Clin Fam Practice. 2002; 4(1).
Stenchever, MA. Comprehensive Gynecology, 4th ed. St. Louis, Mo:Mosby, Inc.; 2001:1217-1250.
U.S. Preventive Services Task Force. Hormone therapy for the prevention of chronic conditions in postmenopausal women: recommendations from the U.S. Preventive Services Task Force. Ann Intern Med. 2005; 142:855-860.
North American Menopause Society. Estrogen and progestogen use in peri- and postmenopausal women: March 2007 position statement of The North American Menopause Society. Menopause. 2007;14:168-182.