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Melanoma of the eye

Definition

Melanoma of the eye is cancer that occurs in various parts of the eye.

Alternative Names

Malignant melanoma - choroid; Malignant melanoma - eye; Eye tumor; Ocular melanoma

Causes

Melanoma is a very aggressive type of cancer that can spread rapidly.

Melanoma of the eye can affect several parts of the eye, including the:

The choroid layer is the most likely location of melanoma in the eye.

The cancer may only be in the eye, or it may spread (metastasize) to another location in the body. Melanoma can also begin on the skin or other organs in the body and spread to the eye.

Melanoma is the most common type of eye tumor in adults. Even so, primary melanoma of the eye is rare.

Excessive exposure to sunlight is an important risk factor. The occurrence of melanoma has greatly increased in recent decades. Fair-skinned and blue-eyed people are most often affected.

References

Damato B. Treatment of primary intraocular melanoma. Expert Rev Anticancer Ther. 2006;6:493-506.

Review Date: 3/24/2008
Reviewed By: Stephen Grund, MD, PhD, Chief of Hematology/Oncology and Director of the George Bray Cancer Center at New Britain General Hospital, New Britain, CT. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

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